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335 Moreover, androgens decrease the type I muscle fibers (TIMF) with highly oxidative and insulin-sensitive properties, while increase type II muscle fibers (TIIMF) that are glycolytic and less insulin-sensitive, further decreasing glycogen synthase expression and favoring the development of IR in PCOS

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10 The likelihood of dysplastic nevi progressing to melanoma is very low, and removing the mole does not significantly lower the risk of developing melanoma

How the dual GLP-1 and GIP mechanism works To understand why a dual agonist outperforms a single agonist, you need to understand what each receptor does independently and what happens when both are activated together