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doi: 10.1016/j.cellsig.2024.111328 28 WangBWangYZhangJHuCJiangJLiYet al

"The melanocortin pathway and control of appetite-progress and therapeutic implications." Journal of Endocrinology

Its improved resistance to degradation also supports studies requiring peptide stability over extended observation periods

The emergence of orforglipron marks what many endocrinologists and pharmaceutical analysts consider the most consequential advance in GLP-1 therapeutics since the approval of semaglutide