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Reduction in Addictive Behaviors: GLP-1 agonists have been shown to reduce cravings and addictive behaviors, which can help with overall lifestyle changes
The RENAAL trial (N=1,513, mean follow-up 3.4 years) showed losartan reduced the risk of doubling serum creatinine by 25% compared to placebo over the long term, demonstrating net kidney protection despite the early apparent rise
As the number of people taking GLP-1s grew, so too did reports about dwindling addictive behaviors
Discussion We demonstrate that chronic tirzepatide treatment reverses obesity-associated increases in body weight, fat mass, and systemic metabolic perturbations, and reduces tumor growth in three murine cancer models
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