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Common side effects include: Nausea Vomiting Diarrhea Stomach pain Constipation Weight loss Serious but less common side effects include: Severe allergic reactions Increased risk of thyroid tumors (including medullary thyroid carcinoma, MTC) Risk of multiple endocrine neoplasia syndrome type 2 (MEN 2) Pancreatitis Diabetic retinopathy complications Hypoglycemia, especially with other diabetes medications Worsening kidney disease Gallbladder disease and gallstones This is not a full list of side effects
Tell your healthcare provider about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements
Tirzepatide generally produces greater average weight loss than semaglutide and is often better tolerated, although both medications have similar gastrointestinal side-effect profiles
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