In a 2018 study published in Current Pharmaceutical Design , researchers compared the effectiveness of BPC-157 to that of various standard peptidergic angiogenic growth factors (EGF, FGF, and VEGF) and numerous carriers for treating gastrointestinal ulcer healing and tendon, ligament, muscle, and bone healing
[8] Moreover, the research team suggested that the peptide may have facilitated the recovery of blood flow in the ischemic muscle of the rat hind limb, as determined by laser Doppler scanning, indicating the compounds potential to promote angiogenesis
Moreover, although Ang-1 and Ang-2 are not known drugs for protecting the glycocalyx, intervening in Ang-1 and Ang-2 may serve as targets for inhibiting glycocalyx degradation
Preclinical studies suggest it modulates nitric oxide pathways and growth-factor expression to promote angiogenesis and collagen deposition in damaged tissues [1] [3]