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Airway remodeling in asthma: what really matters
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showed that ACTL6A was frequently amplified and highly expressed with TP63 and that they coordinated a regulatory on WWC1 to mediate oncogenic YAP activity, contributing to outcomes of patients with head and neck squamous cell carcinoma 11
This is mediated predominantly via CYP3A4/5, with minor contributions from CYP1A2 and CYP2B6
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