Material-enabled lysosomal escape Beyond the pH- and enzyme-responsive mechanisms discussed above, certain nanomaterials possess intrinsic physicochemical properties that enable lysosomal escape through distinct pathways, such as morphology-dependent trafficking, gas generation, or ion-mediated membrane disruption
Pezzola S, Antonini G, Geroni C, Beria I, Colombo M, Broggini M, Mongelli N, Leboffe L, MacArthur R, Mozzi AF, Federici G, Caccuri AM: Role of glutathione transferases in the mechanism of brostallicin activation
CJC1295 is usually administered via subcutaneous injection
For instance, certain peptides can instruct cells to generate more collagen, accelerate recovery, or reduce inflammation