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Adequate hydration and dietary fiber intake help manage this side effect
In the long term, by stimulating GHRH neurons, GHS sustains its receptors by direct effect and also due to association with dopamine receptors to form GHSR1a:DRD2 heteromers 18
Vitamin b12 holds great safety profile and being a water soluble vitamin, it does not accumulate in body so no chance of toxicity is there
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