Whilst biomarker levels of oxidative damage such as 8-hydroxydeoxyguanosine (8-OHdG), lipid peroxidation products [19], and protein carbonyl [20] levels are found to be increased in patients with periodontitis, serum enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxide (GSHPx), and non-enzymatic antioxidants (GSH, vitamins E and C) are found to be significantly lower [19] than healthy control subjects
Abstracts of the retrieved articles were independently screened and assessed to confirm their eligibility by four researchers (GS, AF, SK, AR)
10.1152/physrev.00026.2013 Summary Keywords bridging factors, autophagy, Nrf2-Keap1, TRIM16, SQSTM1, Sestrin2 Citation Ning B, Hang S, Zhang W, Mao C and Li D (2023) An update on the bridging factors connecting autophagy and Nrf2 antioxidant pathway
F., Cabrini, M