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In osteoarthritis, oxidative stress causes excessive ROS in chondrocytes, disrupting the binding of Keap1 and Nrf2, allowing Nrf2 to enter the nucleus, activating the antioxidant response element (ARE), and increasing the expression of antioxidant proteins, such as HO-1 and NQO-1 [69], which can attenuate oxidative stress and inflammatory responses and protect chondrocytes
Fan Z, Cai L, Wang S, Wang J, Chen B
Provitamin A carotenoids from fruits and vegetables carry virtually no risk of toxicity, as your body regulates their conversion to active vitamin A
Randomized placebo controlled study on intravenous L-carnitine supplementation in hemodialysis patients-No benefit in vivo magnetic resonance spectroscopic assessment of muscle [abstract]
