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These two peptides stimulate growth hormone release through two independent receptor pathways : CJC-1295 activates GHRH receptors the same pathway used by your body's natural growth hormone-releasing hormone Ipamorelin activates ghrelin receptors (GHS-R) an entirely separate signaling pathway on the pituitary Stimulating both pathways simultaneously produces a synergistic growth hormone response the combined GH output is significantly greater than the sum of each peptide individually

A novel class of incretin-based therapies consisting of glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) and dual (GLP1/glucose-dependent insulinotropic polypeptide [GIP]) RAs acts by lowering blood sugar and inducing weight loss

Other GLP-1 agonists include dulaglutide (Trulicity), liraglutide (Saxenda and Victoza), exenatide (Bydueron and Byetta), semaglutide (Rybelsus), and tirzepatide (Mounjaro)

70% of Americans believe GLP-1s are only accessible to the wealthy