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They interact with the body in ways that mimic or modulate naturally occurring processes

Supplementary Tables S1 , S2 include a chi-square test for grouped patients, considering the data as a whole

Two points of the regulatory authorisation of orforglipron are worth noting

Across the SURPASS trials documented in the Mounjaro FDA prescribing information, injection-site reactions occurred in approximately 3-7% of participants depending on dose, while true systemic allergic responses (hives spreading beyond the site, facial swelling, breathing difficulty) are rare