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Glutathione IV therapy helps replenish these levels quickly and effectively by delivering the antioxidant directly into the bloodstream

Guided by many promising preclinical studies that potentially link GSH and oxidative stress with the pathophysiology of SZ, multiple groups have also conducted clinical studies and measured GSH levels in peripheral blood of patients with SZ

Alternatively, acetylcarnitine, produced in excess in mitochondria by CrAT, is transported into cytosol by CACT and enters the nucleus, where a nuclear CrAT converts the acetylcarnitine to acetyl-CoA 67 , and it becomes a source of acetyl groups for histone acetylation

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