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Furthermore, evidence from epilepsy models indicates that semaglutide can inhibit the activation of the NLRP3 inflammasome, a multiprotein complex responsible for producing inflammatory cytokines such as IL-1 (Wang et al., 2021)
Clinicians may consider pancreatitis, gallbladder disease, bowel problems, or dehydration-related complications depending on the full picture
In Phase 2 trials, female participants actually achieved slightly higher average weight loss than men at 25.3% versus 22.8% over 48 weeks
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