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Topical gels/creams: Non-invasive but limited absorption
One of the most common symptoms of depression is fatigue, which can be addressed with regular B12 treatments
Their regulatory status ranges from legally compoundable with a prescription (sermorelin) to explicitly restricted injectable formulations (GHK-Cu under the FDA Category 2 list) to regulatory limbo (CJC-1295 and ipamorelin following the September 2024 removal from the 503A compounding bulks list)
Perhaps most telling, researchers tested for anti-AOD 9604 antibodies at multiple timepoints throughout the trials
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