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Starting new exercise routines, increasing walking, or resuming activities that were previously too difficult can cause delayed-onset muscle soreness

Slower titration, meal adjustments, and occasional dose reduction mitigate side effects

One study showed faster walk speed, greater muscle strength measured by handgrip dynamometry and higher fat free mass measured by bioimpedance (adjusted for height squared) in DPP4 users than those on sulphonylureas [147], although it is unclear whether this was due to beneficial effects of DPP4 inhibitors or deleterious effects of sulphonylureas

The loose stools are generally self-limiting and resolve as the body adjusts to supplementation