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For cagrilintide , Phase 2 data has shown meaningful weight loss when used as monotherapy, and the CagriSema combination (cagrilintide plus semaglutide) has entered Phase 3 trials under the REDEFINE programme by Novo Nordisk
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Personalised dietary strategies are particularly relevant considering that, although generally well tolerated, GLP-1RA may cause transient gastrointestinal (GI) symptoms that can hinder adherence if not properly managed [27]
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