tirzepatide semaglutide side effects vs. for Weight Loss: Which Is Right for Me? Are GLP-1s Right For Me?:

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Most people experience initial weight loss during short-term semaglutide use, but clinical evidence shows the majority regain that weight within 6 to 24 months after stopping

The oral formulation (Rybelsus) demonstrates comparable gastrointestinal tolerability profiles

Autoimmunity (2020) 53(6):297302