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Do not use this medication if you are or suspect you may be allergic to any of the ingredients in Contrave including naltrexone and bupropion

Factors that influence early weight loss include starting body weight, baseline diet quality, physical activity level, hydration status, and individual metabolic rate

Targeting the enteric nervous system to treat metabolic disorders

[10] [11] Whilst these medications have proven benefits for glycaemic control and weight loss, their effects on gastrointestinal function mean they can influence digestive symptoms, which is particularly relevant for individuals with pre-existing bowel conditions such as IBS