Don't panic, but if these symptoms persist or worsen, inform your doctor
421,422,423,424,425 Future directions Future translational arterial stiffness research should (i) enhance clinical assessment (e.g., multimodal imaging, wearable-based PWV analysis in large clinical trials and population studies), (ii) identify specific phenotypes and endotypes, (iii) decipher the underlying mechanisms of the use of state-of-the-art technologies (e.g., specific microfluid cell culture systems, machine learning approaches) and new risk factors (e.g., chronic psychosocial stress, air pollution), and (iv) develop tailored prevention and therapeutic approaches (e.g., new pharmacological agents targeting low-grade systemic inflammation, AI-based personalized intervention)
By integrating insights across molecular, cellular, and clinical dimensions, this review offers a strategic framework for understanding and tackling cancer drug resistance, with important translational implications for the future of precision oncology
Santini, S