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Shortcomings of Animal Models : While preclinical data can be suggestive, they do not always accurately predict clinical outcomes in humans due to differences in physiology, disease progression, and complex metabolic interactions that cannot be fully replicated in animal models
doi: 10.1038/s41577-020-0345-y
To exclude that the small spectral changes reflected just a partial glutathionylation, we performed electrophoretic mobility shift assays (Fig
ASS1 downregulation has been reported to be associated with advanced tumor stage, high local recurrence rate, and poor relapse- and metastasis-free survival (Nicholson et al., 2009
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