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As the American Urological Association guidelines on ED note, first-line therapy remains PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil), with bremelanotide not yet included in any major guideline algorithm for male sexual dysfunction [7]

Elevated OAT Candida markers provide objective evidence of yeast activity even when stool culture and antibody tests are equivocal, making it our most sensitive first-line indicator of systemic Candida burden

doi: 10.1016/J.STEROIDS.2023.109185 233

Aggressive Nature and Treatment Challenges of Youth-Onset T2D Youth-onset T2D progresses rapidly, with early onset of complications in adulthood