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Category 2: Associated with significant safety risks: the FDA would consider taking action against a compounder working with a material on this list Category 3: Not enough evidence: the FDA would consider taking action against a compounder working with a material on this list A Note on Alternative Monographs Some substances that are eligible for compounding via inclusion on the Category 1 503A bulks list only have Dietary Supplement monographs, such as methylcobalamin, L-citrulline, and glutathione, among others