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Key research findings include: Average 24.2% body weight reduction in Phase 2 at the highest dose cohort over 48 weeks Significant reductions in waist circumference, triglycerides, and fasting glucose Weekly subcutaneous injection (half-life approximately 6 days) Most common adverse events: nausea, vomiting, diarrhea (typical of GLP-1 class) Requires cold chain storage (28C refrigerated)
Am J Clin Nutr 1992
Weight loss medications like semaglutide and tirzepatide are effective and safe
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