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In people without diabetes, this dual mechanism is generally modest and well-tolerated
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2014: Dulaglutide (Trulicity) is approved by the FDA, and is recognized as the first type 2 diabetes drug to reduce the risk of major adverse cardiovascular events (MACE)
Probiotics are among the key dietary interventions being investigated due to their potential for producing positive effects on gut integrity and thus improving intestinal permeability, which is impaired in some conditions
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