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However, the wear particle-induced aseptic loosening around the prosthesis and subsequent osteolysis can lead to TJA failure and surgical revision [2, 3]
The brain, which is highly susceptible to oxidative stress, possesses a limited capacity to endure such stress owing to its high rate of oxygen utilization, abundant iron content, substantial levels of unsaturated fatty acids, and deficiency in antioxidant defense mechanisms
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