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Inositol's insulin sensitization effect is one reason patients report reduced carbohydrate cravings
TOPI inhibitor-induced SSBs require tyrosyl-DNA phosphodiesterase 1 (TDP1)-mediated excision repair and homologous recombination pathways for repair, so mCRPC tumors harboring HRD may exhibit increased sensitivity to TOPI inhibitor-carrying ADCs 36,37
You will need to recalculate units for the split dose: at 10mg/mL concentration, each 4mg injection is 40 units
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