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Following cerebral ischemia, the substantial release of various cytokines, chemokines and damage-associated molecular patterns (DAMPs) attributes to the activation and recruitment of neutrophils from the bone marrow, spleen, and peripheral circulation to the site of damage ( Table 2 )

Presented for research literature review only Odell WD et al

When to speak to your GP or oncologist Contact your GP, prescriber, or oncology team if you experience: Any new lumps, changes in the affected or unaffected breast, or new symptoms that prompt concern about recurrence Persistent nausea or vomiting that stops you from keeping fluids down Rapid or significant weight loss beyond whats expected Signs of dehydration (dark urine, dizziness, reduced urination) New fatigue that feels different from your post-treatment fatigue Worsening joint pain or new bone pain Increasing anxiety, low mood, or fear of recurrence thats affecting daily life Any difficulty attending cancer follow-up appointments because of side effects Dont delay routine cancer surveillance because of Wegovy

Abd El-Hamid ES, Gamal-Eldeen AM, Eldeen AMS