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To assess the clinical effectiveness of the intervention, the number needed to treat (NNT), an absolute measure of effectiveness, was calculated as the inverse of absolute risk reduction (ARR) as an estimate of the overall clinical impact (NNT = 1/ARR), considering the median of weight reduction in the studied population (2.45 kg) as optimal
1A and Supplementary Table 1)
About 520% of symptomatic gallstone patients undergoing cholecystectomy have choledocholithiasis and the incidence increases with age [180]
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