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Jastreboff and colleagues studied the obesity Phase 2 in NEJM observing mean body weight reduction reaching approximately 24 percent at the 12 mg dose tier at 48 weeks (PMID 37366315)
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Obesity Drugs Are Scaling Fast Apr 22, 2026 Innovation and policy support could more than double sales of GLP-1 medications by 2035
The study included people with cirrhosis, or scarred and permanently damaged livers
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