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doi:10.3803/EnM.2024.1942 2
reactive astrogliosis is fundamentally protective and is indispensable not only for wound closure and formation of a barrier separating fibrotic scar from the healthy tissue but also for postlesional regeneration
Drugs aimed at mTOR (everolimus, metformin), AKT (MK2206), PI3K (buparlisib, rigosertib) are undergoing phase1-3 clinical trials in advanced pancreatic cancer patients (Wolpin et al., 2009
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