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As a glucagon-like peptide-1 (GLP-1) receptor agonist, it works by stimulating insulin secretion, suppressing glucagon, and slowing gastric emptyingmechanisms that do not directly affect urinary frequency
has acted as consultant, advisory board member and speaker for Boehringer Ingelheim, Eli Lilly, Novo Nordisk and Sanofi, an advisory board member Lexicon, Pfizer, ShouTi Pharma Inc, AstraZeneca and Medtronic and as a speaker for AstraZeneca, Napp Pharmaceuticals, Novartis and Amgen
Key symptoms Loose, watery stools Increased frequency of bowel movements Urgency to defecate Abdominal cramping or pain Possible nausea Bloating or gas Risk of dehydration and electrolyte imbalances if severe How common is diarrhoea with GLP-1 treatments
1 Some have theorized that GLP-1 medications may affect metabolic pathways, potentially altering thyroid hormone production
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