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[2] 5-Amino 1MQ is an analogue of the parent molecule 1-methylquinolinium (1-MQ) , modified with a primary amine substitution at the 5-position of the quinoline ring
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5-Amino-1-methylquinolinium iodide is the lead first-in-class small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme overexpressed in white adipose tissue of obese individuals where it consumes the methyl-donor pool and depletes tissue NAD
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