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In vivo animal experiments showed that daily administration of NNMTi for 28 days to dietinduced obese (DIO) mice significantly upregulated the expression of lipolysisrelated genes (such as ATGL and HSL) and downregulated lipogenesisrelated genes (such as FAS and ACC), indicating that NNMTi effectively promotes fat breakdown and inhibits fat synthesis

Current research on 5-Amino-1MQ remains focused on preclinical and laboratory models, where ongoing studies continue to explore its mechanisms and potential experimental applications

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