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doi: 10.1016/j.aaf.2021.10.004 5 Al-HarbiA
However, the interaction with U1-A was not changed, suggesting that the increased binding was not with the whole U1-snRNP complex, which is essential for splice site recognition
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The only reliable indicators are unexpected research outcomes (protocols failing to replicate published results) or specialized potency assays like HPLC (high-performance liquid chromatography) that measure intact peptide concentration
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