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Many studies have reported the neuroprotective effects of UA in cell and animal models of PD
Mild side effects noted in clinical trials have included bloating or mild cramps, gas and/ or loose stools, potential weight gain, and flushed skin
Regions such as the hippocampus and cerebellum are particularly vulnerable to ROS accumulation due to high mitochondrial activity and synaptic demand, whereas frontal cortical areas may exhibit distinct redox buffering capacities
Evidence that hyperglycemia after recovery from hypoglycemia worsens endothelial function and increases oxidative stress and inflammation in healthy control subjects and subjects with type 1 diabetes
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