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The weekly cadence of semaglutide and tirzepatide comes precisely from their being long-acting versions of that natural signal, which the body would otherwise break down in minutes
Clinical trials found about 13.6% average body weight reduction with the oral form and about 14.9% with the injection, though the trials weren't designed for a direct comparison
PMC 178850
They source medications from vetted US-based compounding pharmacies including both 503a and 503b facilities
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