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Persistent and uncontrolled oxidative stress and exacerbating NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome activation during severe COVID-19 disease (Lage et al., 2022), induce production of pro-inflammatory cytokines, such as IL-1 and IL-18, that can be explained because of sharply decreased macrophage GSH intracellular levels associated with increased GSH efflux (Zhang T
Carnitine for Kidney Disease and Hemodialysis Given that the kidney is a major site of carnitine production, damage to this organ can cause a significant carnitine deficiency
10.1111/j.1364-3703.2007.00387.x 143 SellamA.PoupardP.SimoneauP
doi:10.1245/s10434-017-6107-9
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