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This is expected and does not necessarily indicate a problem, but monitoring during the transition is important
61] d, P 0.42) (Supplementary Table S2B)
Tu XK, Chen Q, Chen S, Huang B, Ren BG, Shi SS
| Phase | Dose | Weeks on That Dose | |---|---|---| | Initiation | 0.25 mg weekly | Weeks 1-4 | | First escalation | 0.5 mg weekly | Weeks 5-16 | | Second escalation | 1 mg weekly | Weeks 17-28+ | | Optional third escalation | 2 mg weekly | Week 29 onward | Each dose increase represents a new stimulus to GLP-1 receptors, including those in pancreatic tissue
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