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Short-term exenatide treatment leads to significant weight loss in a subset of obese women without diabetes

In a trial in people with metabolic syndrome, pasteurized Akkermansia increased GLP-1 ( Suenaert et al., 2026 (Human trial)

The serendipitous discovery of exendin-4 led to the development of exenatide immediate-release (exenatide IR, Byetta), a synthetic version of exendin-4 with C-terminal amidation to enhance its stability [ Figure 2 , Table 1 ], which became the first FDA-approved GLP-1RA in 2005 for the treatment of T2DM in adults [ Table 2 ]

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that your body needs for many key functions