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Percentage Achieving Weight Loss Thresholds Key Finding: Both medications get most patients past 20% loss
Two major examples: Hypothalamic-pituitary-thyroid (HPT) axis : Hypothalamus releases TRH anterior pituitary releases TSH thyroid gland releases T3/T4 regulates metabolism Hypothalamic-pituitary-adrenal (HPA) axis : Hypothalamus releases CRH anterior pituitary releases ACTH adrenal cortex releases cortisol regulates stress response Feedback loops are what keep these axes in balance: Negative feedback is the most common mechanism
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