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Lifestyle interventions (including diet, exercise and behavioural changes) are the cornerstone of obesity management with diverse benefits, but even the most intensive lifestyle interventions result in up to 10% mean weight loss (WL) and weight maintenance remains a challenge, as 80% of WL is expected to be regained over the next 5 years [4, 5]
Lingvay I, Deanfield J, Kahn SE, Weeke PE, Toplak H, Scirica BM, et al
USA 114 , 39033908 (2017)
Research by Xu et al
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