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Doses start at 3 mg for the first month, increase to 7 mg, and reach a maximum licensed dose of 14 mg

An open-label dose-response study of lymphocyte glutathione levels in healthy men and women receiving pressurized whey protein isolate supplements

Subsequently, cytochromes P450 (CYP79s) catalyzes the conversion of the amino acid derivatives to aldoximes, oxidized later by CYP83s into nitrile oxides, transformed to thiohydroximates via glutathione (GSH) S-transferases (GSTFs) and the C-S lyase (SUR1) reaction, and finally converted to the GL core structure by S-glucosyltransferases (UGT74s) and sulfotransferases (SOTs) (Figures 35)