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Absence of lot analytical characterisation : a contaminated or mis-dosed lot can invalidate an entire experimental series Preregistration and ARRIVE 2.0 Modern animal research standards require protocol preregistration (OSF, PreclinicalTrials.eu) with ex ante definition of primary, secondary criteria and exclusion rules

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Rechtman, M.M., Har-Noy, O., Bar-Yishay, I., Fishman, S., Adamovich, Y., Shaul, Y., Halpern, Z., Shlomai, A.: Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha

The bottom line is that BPC-157 has real therapeutic potential, but that potential is best realized within a medically supervised framework that prioritizes safety, quality, and individualized care