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Results Patients From February 2013 through December 2013, a total of 4346 patients were screened, and 3297 underwent randomization

Specifically, it is obvious that the newly formed Arg123-Glu40 salt bridge is due to the missense mutation L23B R (Figure 2), i.e., the substitutin of the leucine with a positively charged arginine at position 23 of semaglutides backbone (Figure 2)