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Some studies describe occasional localized redness or mild irritation during topical research applications, while systemic toxicity has not been observed at commonly investigated research concentrations

42 Increased size of the drugs can affect transport as well

NAD+ is a coenzyme present in cellular systems and is studied in laboratory settings as a model compound in research involving redox reactions, molecular interactions, and experimental biological frameworks

Common reported effects in clinical use include mild injection site reactions with subcutaneous administration, occasional digestive changes when taken orally, and rare reports of fatigue or dizziness