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reviews connect NNMT overexpression to obesity, insulin resistance, fatty-liver progression, and other conditions [2,8,9]

Signs of Vitamin B12 Deficiency Some common signs that you may be deficient in Vitamin B12 include fatigue or tiredness, weakness, difficulty concentrating or thinking clearly, pale skin, dizziness or light-headedness, loss of appetite, weight loss, constipation or diarrhea, numbness or tingling in the hands and feet, sore tongue, headaches and vision problems

KPV is also touted as being good for gut health, tissue repair - including skin damage, like acne, and for regulating the immune system

Neither is sufficient alone, neither makes the other redundant