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[8] conducted cDNA analysis of preproglucagon in hamsters, which revealed that mammalian genes differ from those of anglerfish and identified two novel peptides, terming them glucagon-related peptides 1 and 2 (GLP-1, GLP-2)
They are currently licensed only for type 2 diabetes and obesity, and their use in Parkinson's is considered experimental and investigational within clinical trials
Related Stories Genetic variants may help explain who loses more weight and who gets side effects on GLP-1 drugs Semaglutide outperforms other GLP-1 drugs for weight loss in psychiatric populations GLP-1 users say the drugs quiet food noise but do not replace lifestyle change Options include once-weekly injectables, daily agents, combination therapies with insulin, and newer oral formulations that some patients may prefer, although tolerability and discontinuation remain considerations
