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This concept refers to the inherent ability of cells to protect themselves from various forms of damage and maintain their integrity

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Kessler describes it as being "at the edge of nausea." He compares it to the way your stomach might feel when you've eaten a bit too much at Thanksgiving dinner

However, ASS1 is frequently downregulated in fibrotic lung tissues, which promotes fibroblast activation through STAT3 signaling and drives an aggressive, apoptosis-resistant phenotype [87, 88]