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LD50 has not been established because researchers could not achieve lethal doses in standard protocols 1
Women with PCOS typically have elevated androgens, including testosterone, which drives symptoms like acne, excess body hair, and irregular menstrual cycles
Patient-level weight change data were unavailable, so the analysis cannot explain whether the observed differences were driven by weight loss, metabolic control, cardiovascular effects, direct tumor biology, or differences in patient selection
Though there is some concern for irritation from raw or high pH material, a well-balanced formula will be a non-issue for the vast majority of people
